The Washington State Dept. of Agriculture issued an advisory this week that highly pathogenic avian influenza (HPAI) is resurging as migratory birds head south, posing a threat to domestic flocks. Enhanced biosecurity measures are crucial to minimize detections and control disease spread. HPAI H5N1 has been circulating in the US since February 2022, but with a new detection this week in King County. Direct contact with wild waterfowl is a major risk factor. Mammals, including seals, have also been infected. Biosecurity practices such as separating domestic birds from wild ones, indoor feeding, and reporting sick birds are vital. Vigilance is urged to protect poultry, preserve farms, and secure the food supply.